If a woman were taking an acid-suppressing drug such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec) or pantoprazole (Protonix) and then were tested for bone mineral density, she might be found to have osteopenia (early bone weakness) or osteoporosis. The contraindication for taking cefuroxime while on omeprazole is because omeprazole decreases stomach acid which can significantly reduce the amount of cefuroxime in your system. Severe Interactions. Of course—they are safe—but unless you have Zollinger Ellison Syndrome, there’s probably no reason. Your doctor may also suggest you take one at bedtime. The medication is available both over the counter and by prescription. Do not take any medicines on your own. They can increase blood levels of benzodiazepines by interacting with the same liver enzymes that clear them from the body. The FDA warns patients on Plavix not to take Nexium or Prilosec -- or nine other drugs, including Prozac and Tagamet. These medications are not usually taken together. Remember when Zantac, ranitidine was introduced for acid related conditions? Proton pump inhibitors (PPIs) have been associated with several severe, even life-threatening side effects when used frequently over an extended period of time. If pantoprazole is not helping you, you can take ranitidine or gelusil after consulting your gastroenterologist. The over-the-counter dosage is 20mg whereas the prescription version is … Also included on the list of common prescriptions: proton pump inhibitors, such as Nexium and Prilosec. St. John's wort, for example, should not be taken with these drugs. It virtually eliminated peptic ulcer disease—or almost. No studies in patients with GERD demonstrate that the addition of histamine(2) receptor antagonists to twice-daily PPI therapy provides any further benefit above that derived from PPIs alone. The drugs keep Plavix from working properly. While this can help with the symptoms of heartburn whenever you eat a meal, it can decrease the absorption of your thyroid medication causing it not to work as well. Examples of proton pump inhibitors include esomeprazole, pantoprazole, omeprazole, lansoprazole and rabeprazole. These drugs, such as Prilosec (omeprazole), Nexium (esomeprazole), Prevacid (lansoprazole), and Protonix (pantoprazole), are used to treat acid reflux. There are several brand names available over the counter. Omeprazole (Prilosec), Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. What is not Tips. Hello, Prilosec contains omeprazole and both pantoprazole and omeprazole belong to the same group. Prilosec is the brand name for omeprazole, a protein pump inhibitor that is used to reduced the amount of acid in the stomach. 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